Professor, Princeton University,USA
Ileana Cristea is a Professor in the Department of Molecular Biology at Princeton University. Her laboratory focuses on characterizing mechanisms of cellular defense against viruses, and finding new targets for therapeutic intervention. Towards these goals, she has promoted the integration of virology with proteomics and bioinformatics. She has developed methods for studying virus-host protein interactions in space and time during the progression of an infection, which have allowed her group to bridge developments in mass spectrometry to important findings in virology. For example, her laboratory has contributed to the emergence of the research field of nuclear DNA sensing in immune response, and has discovered sirtuins as broad-spectrum antiviral factors. Dr. Cristea is the President of US HUPO, chairs the Infectious Disease initiative of the Human Proteome World Organization, and has acted on the Education Committees of ASMS and US HUPO. She has taught the Proteomics Course at Cold Spring Harbor Laboratory for over ten years, and is Senior Editor for mSystems, Associate Editor for the Journal of Proteome Research, and on the Editorial Boards of Molecular Systems Biology and Molecular & Cellular Proteomics. She was recognized with the Bordoli Prize from the British Mass Spectrometry Society (2001), NIDA Avant-Garde Award for HIV/AIDS Research (2008), Human Frontiers Science Program Young Investigator Award (2009), Early Career Award in Mass Spectrometry from the American Chemical Society (2011), the American Society for Mass Spectrometry Research Award (2012), the Molecular Cellular Proteomics Lectureship (2013), the Mallinckrodt Scholar Award (2015), and The Discovery Award in Proteomic Sciences at HUPO (2017). Her goal and passion for integration of proteomics with biological and clinical studies match well with the overall goal of HUPO, and she has promoted the US HUPO and HUPO organizations for the past 8 years by teaching courses, organizing conferences, and taking leadership roles.
Gilberto B Domont
Emeritus Professor, Federal University of Rio de Janeiro, Brazil
During my lifetime I have acquired experience serving on Boards and Committees of National and International Societies. This experience will be devoted to develop the following Decalogue:
1. Expand and strengthen HUPO current mission and goals.
John McCrea Dickson MD Presidential Professor, University of Pennsylvania School of Medicine, USA
Dr. Benjamin A. Garcia received his B.S. in Chemistry from UC Davis in 2000, where he was an undergraduate researcher with Prof. Carlito Lebrilla. Dr. Garcia then received his PhD in Chemistry from the University of Virginia under the supervision of Prof. Donald Hunt (2005), and then was an NIH Postdoctoral Fellow at the University of Illinois with Prof. Neil Kelleher (2005-2008). In 2008, Dr. Garcia was appointed as an Assistant Professor at Princeton University until his recruitment as the Presidential Associate Professor of Biochemistry and Molecular Biophysics at the University of Pennsylvania School of Medicine in 2012, where he is currently the John McCrea Dickson MD Presidential Professor. Dr. Garcia’s research interest has focused on developing novel mass spectrometry based approaches and computation for interrogating protein modifications, especially those involved in epigenetic mechanisms such as histones. His work has resulted in over 260 publications. He has also been recognized with numerous honors including the NIH Director’s New Innovator Award, the PITTCON Achievement Award, the Ken Standing Award, the Protein Society Young Investigator Award, the American Chemical Society Arthur F. Findeis Award and the American Society for Mass Spectrometry (ASMS) Biemann Medal. Dr. Garcia is on the editorial boards of the Molecular and Cellular Proteomics, and Molecular Omics journals. He also serves on the Board of Directors for US HUPO, serves on the governing council for HUPO (2016-present), and has also served on the ASMS Asilomar Conference and ASMS Diversity committees. He has been heavily involved in chairing sessions, workshops and participating in many US-HUPO and HUPO activities (i.e. Early Career Researcher Initiative). If elected to continue to serve on the HUPO Council, Dr. Garcia would like to develop creative ways to get younger scientists involved in HUPO, and also promote scientific and cultural diversity within the organization.
Associate Professor, Florida A&M University, USA
I have been actively participating in HUPO meetings since 2013 and presented in oral and poster sessions. Since then, I have been active member of HUPO. Several of my undergraduate and graduate students presented their research and benefited from the meetings by developing scientific network. I have been doing proteome research for the past 15 years and published in peer-reviewed journals. I am currently, a reviewer to Journal of Proteomics, Journal of Proteome Research, etc. As a member of the organization, I have developed strong linkages and collaborations with the scientists from various countries, such as Australia, Bangladesh, Canada, France, Japan, India, Iran, Pakistan, US and travelled extensively these places. A society will grow with the teamwork of members, and the elected council. Based on my publications, association with various researchers across the world, and experience as a Principal Investigator I will be able to lead the members and enhance the functioning of the organization. One of my goals to join HUPO council is to link multiple branches of OMICS to PROTEOMICS through HUPO. As an educator and researcher, I have organized conferences and invited national, international speakers to our institution. I successfully participated in the institutional strategic goals. With the above skills and qualities, I am well suited for a position on the HUPO council.
Senior Investigator, Laboratory of Immune System Bilogy, NIAID, NIH, USA
I have served on the HUPO Council since 2017 and I would like to ask for the support from the HUPO community to continue doing so.
I have been working in the area of proteomics and mass spectrometry throughout my professional career. During my graduate studies in Switzerland, I utilized mass spectrometry to study the unusual post-translational modification, the C-mannosylation of the tryptophan residues in proteins. As a postdoc in the US, I worked on PTMs in cell signaling, mapping and determining the site occupancy levels for the O-fucosylation and O-glucosylation sites in Notch receptors and conducting the large-scale studies of the tyrosine phosphorylation dynamics in the protein signaling networks. Currently, I lead the Functional Cellular Networks Section at the Laboratory of Immune System Biology at NIAID, NIH, with the focus on characterizing the changes of protein abundance and PTM status in the innate immune signaling with a goal to be able to create robust, accurate, and predictive mathematical network models.
After joining HUPO, I realized that my professional experience, interests and goals were exceptionally well aligned with these of the HUPO. I enthusiastically support the Organization’s mission and I contribute towards it with my energy and skills. As a Council member I am able to promote HUPO’s mission locally and internationally through intense networking. I am currently the Chair of the Nominations and Elections Committee and I have served as member of the Awards Committee. I have co-organized the US HUPO Annual Meeting in March 2019. I am especially interested in communicating and reinforcing the message that, because proteins constitute the functional cellular machinery, the importance of proteomics as the crucial step beyond gene expression studies should continue to be emphasized to the scientists of all fields! I plan to continue being active in Congress organization and promote proteomics in systems biology.
At the community service level - I am particularly focused on mentoring young scientists who will shape the future of proteomics.
Chief and Senior Scientific Officer, Cancer Biomarkers Research Group, National Cancer Institute, NIH, USA
Dr. Srivastava is a founding member of the HUPO and has since actively participated in HUPO's many programmatic and ground-breaking programs, such as the Plasma Proteome Project, Liver Proteome Projects, Glycoscience, Biology and Disease HPP projects, etc. His commitment to HUPO and his breadth of science management, visions in proteomic research and leadership skills are abundantly visible. In addition, Sudhir is responsible for launching of the US National Cancer Institute (NCI’s) flagship initiatives on diagnostics assays, protein biomarkers, liquid biopsy, biomarkers and imaging, glycomics, and organ-specific, congressionally-mandated initiatives on pancreas and liver. He now leads efforts on building the pre-cancer genome atlas as part of the NIH Cancer Moonshot initiatives. While spearheading many outstanding, highly productive biomarker research programs at the NCI, he has heralded a new era of translational research in biomarkers for early detection of cancer. In many ways his science management skill and visions for biomarker research have led to concept of precision detection, prevention and treatment, which are at the forefront of cancer treatment.
He has edited a highly acclaimed book on Informatics in Proteomics, helped develop several FDA-approved protein-based biomarkers for early detection of cancer, and convened many high-level collaborations on proteomics internationally, e.g., China, Japan, India, Chile, UK and France.
By serving on the HUPO's Council, he will bring his invaluable management experience and scientific perspectives on proteomics with valuable resources, intellectual capital and research platforms for conducting research on biomarkers. His role as HUPO Strategic Scientific Initiative Chair will provide funding bodies to engage with HUPO members on proteome centric driven programs that are mutely beneficial. With your support, as a member of the HUPO Council, Sudhir plans to expand the councils outreach to bring more support to HUPO, and provide guidance to the ever-important role that HUPO plays in proteomics research.
Professor, Univ of Texas Health Science Center San Antonio, USA
I have been actively engaged in biomedical mass spectrometry since the early 1970’s, analyzing “small” molecules until the late 1990’s when my efforts shifted to proteomics. During this period, I have frequently participated as chair for review of NIH national (proteomics and glycomics) MS resources and grant applications for major instrumentation funding. After serving on the Editorial Board of the Journal of Proteome Research starting in 2007, I became an Associate Editor for the journal in 2011 and focus on informatics and MS technology. Previously, my scientific society activities were predominantly with the American Society for Mass Spectrometry (ASMS). I was elected to the Board of Directors as Secretary and then Member-at Large for Publications and subsequently served a six-year term as VP Programs, President and Past-President. Following that commitment, I have now had the time to become involved in various aspects of HUPO. My main efforts have centered on the HPP, as the chair of the MS Resource Pillar and member of the Executive Committee. During the past two years, the MS Resource Pillar has been conducting a "phosphopeptide challenge," and the committee is currently compiling the results from phosphopeptide sample analysis by HUPO members for presentation at the 2019 conference. I have also had the honor of serving on the HUPO Council for the past three years and value the opportunity to attend the annual Council meeting and provide input to the officers for future HUPO initiatives. I am submitting this nomination in the hopes of serving another three-year term on the Council. I would like to see Council members have more involvement in the society than just attending one meeting a year. I am also very interested in capitalizing on my many years of experience in education and in scientific publishing for the benefit of HUPO.