Péter Horvatovich, University of Groningen, Netherlands
The Newsletter summarizes all C-HPP related news and activities from May 2018 to July 2019. The Newsletter starts with the Editorial of Christopher Overall, C-HPP Chair, summarizing the current status of the international efforts to find evidence on missing proteins (PE2-4), making c.a. 89% completion and future direction of neXt-CP50. Next, the article entitled “Services for cDNA clones: New Resources for the Dark Proteome Research” by Joshua LaBaer presents the world’s largest collection of unique, full-length Gateway plasmids representing more than 89% (covering 17,362 unique genes) of 19,522 human protein-coding genes made by the chromosome 10 team. These clones and the cloning facility to prepare new clones for sequence variants are available at Arizona State University and can be used to prepare recombinant proteins that can support both confirmation of missing proteins and functional characterization of uPE1 proteins.
The Newsletter also gives highlights on recent C-HPP Workshops such as the 19th C-HPP workshop in Santiago, Spain, June 16-17, 2018, the 20th HPP Post-Congress Workshop as follow-up of HUPO 2018, in Orlando, USA on October 4, 2018, and the 21st C-HPP Workshop entitled “Illuminating the Dark proteome”, Saint Malo, France, May 11-14, 2019. Besides workshop highlight organizational changes such as introduction of new neXt-CP50 program, election of new (co-)chairs and chromosome PIs. The update of the neXt-MP50 project documented the evidence for new candidates of 104 MPs, which are listed in the Editorial of JPR 2018 issue. Also other highlighted are the summary on JPR 2018 special issue, plans for the 23rd HUPO C-HPP HPP symposium (C-HPP2020) "From chromosome-centric project to the human proteome" which will be taking place in Russia from 22 to 26 May, 2020. This workshop will be happen aboard on a ship traveling from Saint Petersburg to Valaam Island and back.
Click here to view the C-HPP Newsletter No.8.