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Newsletter of the Human Proteome Organization

Current and past HUPOSTs are posted here for your review. Stories, highlights, news, and announcements are gladly accepted for inclusion in the HUPOST. Please submit your information to the HUPO Office at office@hupo.org.


  • 31 Oct 2019 4:26 PM | Anonymous member (Administrator)

    Vera Ignjatovic,University of Melbourne, Australia

    Blood plasma is a highly accessible sample for monitoring the health status of a donor and is, as such, one of the most frequently analyzed specimens for clinical testing. Plasma is therefore a sample type that is also very frequently used in translational research. However, it is a challenging sample for proteomics analysis because a small number of proteins are extremely abundant, making it difficult to assay the very many lower abundance proteins.

    The Human Plasma Proteome Project (HPPP) was launched in 2002 as one of the first initiatives of HUPO with the main aim of uncovering the complexities and defining the protein contents of this key reporter system.

    Today, the HPPP initiative is led by Jochen Schwenk, Eric Deutsch and Vera Ignjatovic a group of proteomics researchers with diverse focus areas. Similar to the body fluid it studies, HPPP is a connecting platform that has collaboration at its core. This became evident in a recent article produced by a multinational and multidisciplinary team of early career researchers, representatives from the industry and senior members of the community.

    The HPPP also aims to support early carrier researchers (ECR) such as Philipp Geyer, who has implemented the rectangular strategy and is working on biomarker discovery in Matthias Mann´s laboratories in Munich and Copenhagen. Philipp joined the HPPP for a plasma proteomics review published in the Journal of Proteome Research last month, allowing him to work in an interactive team of highly experienced proteomics researchers.

    [Ignjatovic V, Geyer PE, Palaniappan KK, Chaaban JE, Omenn GS, Baker MS, Deutsch EW, Schwenk JM. Mass Spectrometry-Based Plasma Proteomics: Considerations from Sample Collection to Achieving Translational Data. Journal of Proteome Research]

    HPPP wants to support the community and reflect on the recent improvements in the depth, coverage and speed of studying plasma proteins - either via MS-based approaches or affinity assays. A revived interest in this clinically valuable proteome is accompanied with an increase in the number of MS data sets available to the public, as well as increasing availability of large-scale affinity proteomics data. In addition, links to other omics data types will help to uncover the currently less well understood processes in health, disease, and ageing. The growing resources to build targeted MS as well as affinity-enhanced assays will further expand our understanding of the plasma proteome.

    The HPPP seeking researchers engaged in plasma proteomics projects or anyone interested in advancing the state-of-the-art in plasma proteomics in the future to join the HPPP team. Please contact any of the above co-authors and state your interest in joining this project.

  • 08 Oct 2019 11:37 AM | Anonymous member (Administrator)

    Early Career Research (ECR) Committee

    ECR competition winners
    The ECR initiative would like to congratulate Eneko Villanueva (University of Cambridge) who won the ECR Manuscript Competition with his talk on the “Comprehensive identification of RNA–protein interactions in any organism using orthogonal organic phase separation (OOPS)” and Tim Van Den Bossche (Ghent University) who won the Ph.D. Poster Competition with his presentation entitled “ReScoring peptide-to-spectrum-matches based on predicted fragment ion intensities leads to an increased identification rate in metaproteomics”. The ECR initiative also congratulates all finalists of both competitions, who were invited by the Royal Society of Chemistry to a networking dinner, where they had the opportunity to learn about the publication peer review process. Finally, thank you to all senior scientists who participated in the review process for these competitions.

    Fourth from the left Maggie Lam (Runner-up), Enek Villanueva (Winner), and Ankit Sinha (Runner-up).

    HUPO 2019 PH.D. Poster Competition Recipients 

    Fourth from the left Tim Van Den Bossche (Winner), Sayantani Chatterjee (Runner-up) and Maik Mueller (Runner-up).

    Annual Mentoring Day and networking event
    In addition to displaying their proteomics research on the international stage, ECRs had the opportunity to participate in the annual HUPO Mentoring Day, where they gathered advice on how to communicate, manage and network effectively from international proteomics leaders. The ECR initiative thanks Drs. Jennifer Van Eyk, John R. Yates III, Birgit Schilling, Daniel Figeys, Merry Lindsey, and Stuart Cordwell for sharing their experience with the future leaders of the field. Furthermore, over 30 ECRs also had the occasion to mingle at a meet and greet breakfast session generously sponsored by Atturos.

    Thank you for supporting ECRs
    Finally, the ECR initiative would like to thank Prof. Peter Hoffmann and Prof. Stuart Cordwell, the entire organizing committee of the HUPO 2019 World Congress in Adelaide and HUPO for deploying herculean efforts to offer travel funding for ECRs to attend HUPO 2019. Through their work and by reaching out to local communities, they were able to provide travel funding to over 150 ECRs. The ECR initiative would also like to thank the following societies (in no particular order) who partnered to provide travel funding to ECRs: the German Society for Proteome Research (DGPF), the Japanese Proteomics Society (JPrOS), the Korean Human Proteome Organization (KHUPO), the Proteomics Society of India (PSI), the Singapore Society for Mass Spectrometry, the Swiss Proteomics Society, the United States Human Proteome Organization (US-HUPO), and the Australasian Proteomics Society (APS).

  • 08 Oct 2019 10:58 AM | Anonymous member (Administrator)

    Chris Overall (Chair), Young-Ki Paik (Co-Chair), Lydie Lane (co-chair), Gilberto B. Domont (MAL), Fernando Corrales (MAL), Pengyuan Yang (MAL) and Péter Horvatovich (Secretary General).

    The Annual HUPO Congress in 2019 in Adelaide, Australia had a rich C-HPP and HPP program and activities on the future directions of the (C-)HPP programs.

    The HPP investigators day, September 16, 2019

    The HPP investigators Program was held on Sunday, September 15, 2019. The program included a long introduction to “The Human Proteome Project” by Mark Baker, followed by updates and reports on C-HPP and JPR HPP special issue by the C-HPP Chair, Chris Overall, the B/D-HPP by Fernando Corrales, Knowledgebase Pillar by Eric Deutsch, Mass Spectrometry Pillar by Sue Weintraub, Antibody/Affinity Pillar by Jochen Schwenk and the fourth new Pathology Pillar by Dan Chen.

    The program was followed by C-HPP and B/D-HPP Principal Investigator Council meetings in parallel sessions and then by the HPP Workshop on “Illuminating the dark proteome to understand human biology and disease”, where Eric Deutsch presented the HPP Data interpretation Guidelines version 3.0 and Lydie Lane provided an update on new neXtprot developments, such as the support of the PSI Extended Fasta Format (PEFF), which includes annotation of the protein sequences with PTMs and sequence variants using controlled vocabulary, changes on protein evidence levels, definition of protein function serving the basis of uPE1 definition and changes of the number of proteins with known and unknown functions in the current neXtprot release (Jan-2019) compared to the previous release in Jan-2018, integration of variant frequencies from gnomAD database and the future integration of I-TASSER/COFACTOR protein function predictor tools.

    Paola Roncada provided a summary on the Food and Nutrition Proteomics highlighting importance of proteomics in allergen identification such as partially digested shrimp tropomyosin. The Human Kidney and Urine proteome initiative progress was presented by John Arthur, while Meggie Lam presented the PubMed literature analysis of the HPP completed with visualization using VOSviewer.

    HPP Workshop Day, September 19, 2019

    HPP Workshop day started with an intensive and animated discussion on the highlights of HUPO 2019 and current progress and future directions of the HPP by Jennifer van Eyk. Then the future directions of the HPP was highlighted by C-HPP EC by Chris Overall and Young-Ki Paik, B/D-HPP (Ileana Christea), the Pathology Pillar (Dan Chan), and Ab/Affinity Pillar, by the new Chair, Cecilia Lindskog. Discussion led to the presentation of current and future HPP Pillars plans and how to increase in general the visibility of proteomics in the scientific community.

    Th eSPecial Invited C-HPP speaker, Seán O’Donoghue, presented an illuminating lecture on the “The dark proteome of structural biology”, where “dark” represent regions in proteins where there is no known or predicted structure based on every sequence with a structure in the PDB from all species, a brilliant tour de force in bioinformatics and data visualizations using the AQUARIA tool. Missing protein searches in rare tissues such as human bone was summarized by Chris Overall leading to uncomfortable conclusions concerning the likelihood of finding MPs in such tissues, while Fernando Corrales summarized popular and less popular proteins in disease.

    Mike Snyder presented a multi-omics strategy of human health over several years of active monitoring and Lydie Lane the use of SPARQL to query multiple complex databases among others neXtProt allowing to gain more comprehensive information on life-science curated data as strategy for better HPP outreach.

    C-HPP Poster Session

    Three winners of the C-HPP Poster Awards each received a certificate and cheque of USD200 from John Wilson, Protifi at the closing ceremony. The awardees are, Chae-Yeon Kim (Yonsei University, Seoul, Korea), Chengxin Zhang (University of Michigan, Ann Arbor, MI, USA) and Yuanling Zhang, (Siqi Liu Lab, Beijing Institute of Genomics, China).

    Bioinformatics Hub

    Again, Eric Deutsch has mastered a wide ranging and practical program on bioinformatics challenges in MP hunting, data analysis and implementing the new Human Proteome Project Data Interpretation Guidelines (Version 3.0) in a friendly atmosphere that encourages Q & A and for attendees to come away truly knowing the answer to their questions. The program with some of presentations is available at http://bit.ly/hupohub2019.

    The C-HPP Wiki

    The C-HPP wiki was updated with slides of many presentations and a dedicated session of the Bioinformatics hub was provided on how to edit C-HPP Wiki, which is based on Tiki Wiki content management system (version 18.1). We ask input from the individual chromosome teams to fill the C-HPP Wiki with further content regarding resources, achievements, available ProteomeXchange datasets and any information, which is relevant for C-HPP participants and in general for the HPP community.

  • 08 Oct 2019 10:50 AM | Anonymous member (Administrator)

    Michelle Hill, QIMR Berghofer Medical Research Institute, and The University of Queensland, Australia

    Submit your original research, communications or review manuscripts that combine proteomics with other omics techniques to this special issue by 31 May 2020. Find out more here: https://www.mdpi.com/journal/biomolecules/special_issues/multiomics_biomedical_research

  • 08 Oct 2019 9:53 AM | Anonymous member (Administrator)

    Michelle Hill, QIMR Berghofer Medical Research Institute, and The University of Queensland, Australia

    The laid-back city of Adelaide provided a relaxing backdrop for an intensive week of HUPO2019 - a big thank you and congratulations to the local organizing committee!

    In addition to cutting edge science, HUPO Executives, HUPO Council and Presidents of National Proteomics Societies had extensive discussions on future strategies for HUPO. Several areas of development were identified, including:

    • Foster active HUPO community on social media.
    • Add value to HUPO membership and attract new members.
    • Inform the broader public on the importance of proteins.

    It is envisaged that small groups of volunteers will drive specific tasks towards the identified goals, generally within short time frames. We would like to invite members with practical ideas and time to volunteer through this online form. Feedback on current barriers and potential drivers to increase the engagement can also be provided through the same.

    Early Career Researchers (PhD students and postdocs) are particularly encouraged to help build our HUPO community!

  • 30 Aug 2019 11:48 AM | Anonymous member (Administrator)

    Early Career Research (ECR) Committee

    The HUPO ECR committee has an open position for a member at the post-doctoral fellow or junior faculty level. This member would be responsible for the communications of the initiative. The member’s tasks would include, but not limited to:

    • Interacting and participating with the ECR committee to grow and support proteomics for early stage investigators.
    • Maintaining and upgrading the HUPO ECR website,
    • Managing the HUPO ECR social media accounts (Twitter, Facebook, Instagram),
    • Assembling material for the HUPO HUPOST monthly emails.
    • Participating in the planning ECR events at International HUPO and other HUPO related events.

    In addition, the member would be expected to participate to the monthly calls with all committee members.

    This position represents a fantastic opportunity for early career researchers to network with other junior scientists and also several senior leaders in the Proteomics field. The member will also have the occasion to develop his own leadership and management skills in an international organization.

    The member should be ready for a commitment of two years to the ECR initiative.

    Interested candidates can contact Mathieu Lavallée-Adam (mathieu.lavallee@uottawa.ca) if they have any questions or to signify their interest before September 8th. It should be noted that the ECR initiative is committed to equity, diversity and inclusion principles and that these, along with geographic diversity will be considered to fill this position.

  • 30 Aug 2019 11:16 AM | Anonymous member (Administrator)

    Early Career Researcher Committee

    The Early Career Researcher (ECR) initiative has prepared numerous exciting activities for the upcoming HUPO World Congress. The following activities will highlight ECR talents and provide junior scientists with unique development opportunities.

    1. All ECRs are invited to register and attend the ECR Mentoring Day on September 15th, where they will interact with senior mentors and learn how to communicate, manage and network more effectively. For more information, please visit: https://www.hupo2019.org/mentoring-day-2/

    2. The three finalists of the Early Career Researcher Manuscript Competition will be giving talks at the World Congress. Come hear about their research during the following sessions:

    • Bioinformatics and Statistics, (Maggie Lam - Sept 17, 10:40AM – 12:40PM),
    • Proteogenomic, (Ankit Sinha - Sept 17, 3:15PM - 5:15PM)
    • The Interactome (Eneko Villanueva - Sept 18, 1:30PM - 3:30PM).

    For more details about the finalists, please visit: https://hupo.org/Early-Career-Researcher-Competition-2019

    3. The eight finalists of the Ph.D. Poster competition will be giving short talks in Adelaide. All are invited to discover their work. The competition finalists are listed here.

  • 30 Jul 2019 4:51 PM | Anonymous member (Administrator)

    Péter Horvatovich, University of Groningen, Netherlands 

    The Newsletter summarizes all C-HPP related news and activities from May 2018 to July 2019. The Newsletter starts with the Editorial of Christopher Overall, C-HPP Chair, summarizing the current status of the international efforts to find evidence on missing proteins (PE2-4), making c.a. 89% completion and future direction of neXt-CP50. Next, the article entitled “Services for cDNA clones: New Resources for the Dark Proteome Research” by Joshua LaBaer presents the world’s largest collection of unique, full-length Gateway plasmids representing more than 89% (covering 17,362 unique genes) of 19,522 human protein-coding genes made by the chromosome 10 team. These clones and the cloning facility to prepare new clones for sequence variants are available at Arizona State University and can be used to prepare recombinant proteins that can support both confirmation of missing proteins and functional characterization of uPE1 proteins.

    The Newsletter also gives highlights on recent C-HPP Workshops such as the 19th C-HPP workshop in Santiago, Spain, June 16-17, 2018, the 20th HPP Post-Congress Workshop as follow-up of HUPO 2018, in Orlando, USA on October 4, 2018, and the 21st C-HPP Workshop entitled “Illuminating the Dark proteome”, Saint Malo, France, May 11-14, 2019. Besides workshop highlight organizational changes such as introduction of new neXt-CP50 program, election of new (co-)chairs and chromosome PIs. The update of the neXt-MP50 project documented the evidence for new candidates of 104 MPs, which are listed in the Editorial of JPR 2018 issue. Also other highlighted are the summary on JPR 2018 special issue, plans for the 23rd HUPO C-HPP HPP symposium (C-HPP2020) "From chromosome-centric project to the human proteome" which will be taking place in Russia from 22 to 26 May, 2020. This workshop will be happen aboard on a ship traveling from Saint Petersburg to Valaam Island and back.

    Click here to view the C-HPP Newsletter No.8.

  • 29 Jul 2019 3:06 PM | Anonymous member (Administrator)

    Vera Ignjatovic,University of Melbourne, Australia

    With the HUPO 2019 Congress fast approaching in the table below we present a compact guide of the variety of B/D-HPP activities taking place and urge the HUPO attendees to schedule these in their congress calendar.

     Day  Event  Summary  Timing  Location

    14th September 

    2nd Australasian Glycoscience Symposium Exciting opportunity to further strengthen the bridge between the Glycosciences and Proteome research.

    08:30 to 17:30

    HB Building (L8) UniSA, North Terrace, Adelaide, Australia
    14th September  Human Immunopeptidome (HIPP) satellite This meeting will bring together leading scientists from academia and industry to showcase their latest findings in the field of immunopeptidomics.

    08:30 to 17:15

    Adelaide Convention Centre
    15th September  HPP Investigators Program Annual HPP workshops to assess and accelerate progress on the major components including the Chromosome-centric HPP teams (C-HPP), Biology and Disease-based HPP teams (B/D-HPP) and the Resource Pillars for Antibody/Affinity Reagents Profiling, Mass Spectrometry, Knowledgebases and Pathology. 08:00 to 15:30 Adelaide Convention Centre
    15th September Cancer Biomarkers meeting This meeting will focus on understanding the issues related to biospecimens, statistical designs, experimental plan and data interpretation toward robust and reproducible biomarkers that can meet regulatory requirements. 12:30 to 15:30
    Adelaide Convention Centre
    16th to 18th September  Bioinformatics hub HPP-related topics included amongst other topics http://bit.ly/hupohub2019for schedule. Check the congress program Exhibit Hall Adelaide Convention Centre
    16th to 18th September  HPP concurrent/parallel sessions

    6 thematic sessions

    1. Towards the Complete Cardiac Proteome and Beyond.
    2. Rheumatic and Autoimmune diseases.
    3. P3: Plasma, Pediatrics and Proteomics.
    4. Pathology and the Cancer Proteome.
    5. Neuroproteomiics at the interface of bench to bedside.
    6. Moving proteomics into pharmaceutical discovery and application.

    Check the congress program

    Adelaide Convention Centre

    19th September Post-Congress HPP (Future) Workshop This HPP Workshop follows the HUPO2019 Congress and will focus on exciting developments in human proteomics and strategic planning for the Human Proteome Project. 09:00 to 17:00 Bradley Forum Ϯ Level 5 Hawke Building, City West Campus, UniSA, 50-55 Nth Terrace, Adelaide

  • 29 Jul 2019 2:13 PM | Anonymous member (Administrator)

    Justyna Fert-Bober, Cedars-Sinai Medical Center, USA

    Adelaide, Australia (September 15, 2019) — The HUPO World Congress is proud to announce the Fifth Annual International Mentoring Day on September 15, 2019.

    If asked to name a mentor that has helped to shape you, would you be able to identify one? What are your expectations of such a mentor? What characteristics define a remarkable mentor? As a mentee what can you offer to your mentor? These questions and more, will be discussing during the HUPO Mentoring day.

    The focus of the annual Mentoring Day being held during the HUPO World Congress 2019 is on mentor-mentee relationship and how to establish productive networks needed for early career scientists. This year, the program covers the following topics:

    1. Mental and Health Wellness - Yours and the people around you.

    2. The art of self-promotion and lab-promotion.

    3. Bad manuscript review, bad grant review. - How to respond to them!

    4. Selling proteomics and bioinformatics to scientists outside the field

    During this workshop, mentees will meet and interact with a stellar group of mentors that have established themselves as international leaders in proteomics, including (in alphabetic order): Dr. Stuart Cordwell (Australia), Dr. Daniel Figeys (Canada); Dr. Martin Larsen (Denmark), Dr. Merry Lindsey (USA), Dr. Birgit Schilling (USA) and Dr. Jennifer Van Eyk (Canada/USA).

    Each mentor is coming from different cultural and sociological background. They all took different pathways to become PIs, but they all have one thing in common, they are all passionate about sharing their experience with early career scientists. This workshop promotes face-to-face discussions, friendly roundtable exercises and lots of career advice. Self-promotion is a very subtle art. It requires building relationships, and this workshop is an excellent opportunity to start creating new ones.

    Please see below our mentors’ biographies:

    Stuart Cordwell is a professor of Analytical Chemistry at the University of Sydney, who has co-supervised 16 PhD students and more than 20 Honours students. Stuart obtained his PhD at the University of Sydney. He was an author on the manuscript that defined the term ‘proteome’ in 1995 and has been involved in proteomics research throughout his career. He also established the first laboratory-based undergraduate Proteomics course in Australia. Dr. Cordwell’s vision for the Australasian Proteomics Society is to provide an inclusive society and support network that encourages the participation of Early and Mid-Career Researchers, as well as providing financial and travel support for students and consistent high-quality meetings of international standard.

    Quote: ‘Get angry, get emotional, channel the energy into your reply; then sleep on it, consider it, remove the emotion and your argument will be strong’

    Daniel Figeys is professor in the Department of Biochemistry, Microbiology and Immunology at the University of Ottawa. He is the founding director of the Ottawa Institute of Systems Biology and is the co-founding director of the Shanghai Institute of Materia Medica-University of Ottawa Joint Center in Systems and Personalized Pharmacology. Dr Figeys obtained his Ph.D. in Chemistry from the University of Alberta and did his postdoctoral studies at the University of Washington in Molecular Biotechnology. Daniel was previously Senior Vice-President at MDS-Proteomics and more recently co-founded MedBiome and Biotagenics, two early start-up biotech companies. His laboratory has published over 180 papers and has been cited over 14,000 times. Through starting new companies and transferring technology to industry Daniel has experience in “Selling the power of proteomics and bioinformatics to scientists outside the field”. He is also responsible for a professional skill development program that amongst other skills includes wellness, networking and self-promotion.

    Quote “I wish these types of training had been available when I was a student/postdoc instead of having to learn on the fly”

    Merry Lindsey is Chair of the Department of Cellular and Integrative Physiology and Founding Director of the Nebraska Center for Heart and Vascular Research (NE-CHVR). Her research is focused on using proteomics to understand extracellular matrix responses to cardiac injury. Specifically, her lab develops multidimensional approaches to examine the mechanisms whereby the left ventricle responds to injury with the goal to develop therapeutic strategies to prevent, slow, or reverse the progression to heart failure. She is also dedicated to disseminating scientific results to the general, scientific, and medical communities and educating the next generation of scientists. Dr. Lindsey serves as Deputy Editor for the American Journal of Physiology- Heart and Circulatory Physiology and is on the editorial boards for Circulation Research and Basic Research in Cardiology. She is actively involved in the American Physiological Society, the American Heart Association, and the American Society of Matrix Biology and has presented her research at over 150 national and international venues. Her trainees routinely publish high impact articles, win research awards for excellence, and successfully transition to independent faculty positions.

    Quote: The trick to answering reviewer comments is to make sure future reviewers can never make the same comment

    Rob Rivers is a Program Director at the United States National Institute of Diabetes and Digestive and Kidney Diseases which is a part of the National Institutes of Health. He holds a Ph.D. degree in Chemistry from the University of Cambridge and a B.S. degree in Chemistry from Kentucky State University. In his current role he funds graduate students and post-doctoral fellows, as well as managing programs designed to foster the recruitment and training of minority and underrepresented biomedical investigators. Dr. Rivers trained early graduate students and early stage investigators on the importance of clear communication for promotion of science as well as ensuring wellness both physically and mentally.

    Previously he worked at as Program Official at the Office of Cancer Clinical Proteomics Research with a focus on funding proteogenomic research on colon and ovarian cancers. He is active in the local and global community and was instrumental in starting the international non-profit organization Umbrella Initiatives Foundation that helps in providing improved educational opportunities to children living in poverty in Peru, Bolivia and the United States (www.umbrellainitiatives.org).

    Importance of Wellness:
    “Physical and mental wellness is integral in sustaining research pursuits over one’s career. When we don’t look after ourselves, then the quality of our work will decline as well.”
    -Rob Rivers

    Quote If you don’t have time for wellness, then sooner or later you will be making time for illness.
    -Adapted from Edward Stanley

    Brigit Schilling is an Assistant Professor and the Director of the Mass Spectrometry Core at the Buck Institute for Research on Aging in California, with an Adjunct Professor appointment at the University of Southern California (USC). The Schilling lab develops and implements innovative protein analytical technologies to advance basic biology and biomedical research related to aging research. Research projects include investigation of protein phosphorylation, acetylation, and other posttranslational modifications, as well as differential expression of proteins during disease and aging processes. The Schilling lab has been highly successful in adopting novel proteomic technologies to achieve comprehensive and sensitive quantification capabilities. Dr. Schilling has mentored several postdoctoral fellows and research associates and provided strong support for them to achieve their career goals and offer them opportunities, such as attending conferences and educational courses.

    Quote: Sharing scientific ideas with others and being able to discuss and present posters or talks at conferences is a big step towards building your own scientific network and establishing contacts that can be fostered throughout your career.

    John R. Yates is an American chemist and professor of chemical biology at The Scripps Research Institute in La Jolla, California. His work is focused on developing tools and in proteomics and he specializes in mass spectrometry. Dr. Yates III is the recipient of the 2019 ASMS John B. Fenn Award for a Distinguished Contribution in Mass Spectrometry, for development of automated, large-scale interpretation of peptide tandem mass spectral data. Dr. Yates’ SEQUEST algorithm laid a critical foundation for the field of proteomics and has enhanced the accuracy and effectiveness of mass spectrometry to understand important biological and clinical questions. He also received the Thomson Medal in 2018. He has trained MSc/PhD students, post-doctoral fellows and PhD students. His strengths in leadership and mentoring help many to transited into independent faculty positions

    Quote: Every 4-5 years you have to throw yourself onto the job market to see what you’re worth.

    Jennifer (Jenny) Van Eyk is a Professor of Medicine at Cedars-Sinai Medical Center, Director of the Basic Science Research in the Barbra Streisand Woman’s Hearth Center and Director of the new Advance Clinical Biosystems Institute that has the motto “from discovery to patient care”. She co-director of the Cedars Sinai Precision Health, focused on in-hospital and population individualization of health care. Dr. Van Eyk is an international leader in the area of clinical proteomics and her lab focuses on developing analyical pipelines for de novo discovery and large-scale quantitative mass spectrometry methods. The aim is to maximize throughput and reproducibility to move targeted and robust discovery methods into continuous large population assessment and to develop clinical grade assays for neurological and cardiovascular diseases. To this extent she, oversees the new Cedars-Sinai Precision Biomarker Laboratories which consists of the Translational and CAP/CLIA certified clinical lab.

    Dr. Van Eyk was a technician prior to obtaining her PhD from the University of Alberta (Canada) and doing her postdoctoral research in Heidelberg and University of Illinois in Chicago. Her first faculty position was at Queen’s University in Kingston Canada where she started her first company. She was recruited to Johns Hopkins University and then to Cedars-Sinai Medical Center. She has mentored over 30 graduate students and post-doctoral fellows who are now successful in many different science-related jobs.

    Quote: Fill your life and lab with wonderful amazing people and create an environment where they can become the best they can be.

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