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Human Brain Proteome Project




The Human Brain Proteome Project (HBPP) is an initiative aimed  towards unveiling the brain proteome. In the 2015 HUPO meeting, the HBPP renewed its steering committee and is now defining new tasks for its future. This includes large-scale and targeted state-of-the-art proteome studies on human brain, brain-related body fluids such as CSF, pre-clinical models and follow up projects to decipher the role of proteins in brain development, health and disease.

Current lines of work:

  • Integrate neuroproteomic scientists
  • Identify molecular mechanisms and biomarkers involved in neurodegeneration and psychiatry
  • Understand the environment around the healthy human brain
  • Develop new strategies and methodological approaches for neuroproteomics

HBPP Steering Committee

  • Katrin Marcus (Chair) Ruhr University, Bochum
  • Charlotte Teunissen (Co-chair) VU University Medical Center Amsterdam
  • Lea Grinberg, University of California San Francisco 
  • Daniel Martins-de-Souza, University of Campinas, São Paulo 
  • Helmut E. Meyer, ISAS – Leibnitz-Institut für Analytische Wissenschaften, Dortmund 
  • Peter Nilsson, KTH – Royal Institute of Technology, Stockholm 
  • Young Mok Park, Korean Basic Science Institute, Daejeon
  • Oliver Schubert, University of Adelaide 

Award For Prof. Daniel Martins-De-Souza

Serrapilheira Institute is the first private nonprofit institution created to promote science and increase its visibility and impact in Brazil.

Their first call was directed to identify and support the best young researchers in Brazil. According to its President, Dr. Hugo Aguilaniu, they looked for those who are posing the big questions in their fields.

There were almost 2000 submitted projects, from which they selected 65. These will receive R$ 100,000.00 (near US$ 31,000.00) for one year. The Institute will selected 10 to 12 out of the 65 to receive R$

1 million (near US$ 310,000.00) for additional three years.

Daniel Martins-de-Souza, member of the HBPP steering committee, is one of the 65 awardees. His project uses neuroproteomics to understand the molecular basis of schizophrenia and to identify protein biomarkers in patients´ blood which could predict antipsychotic response.

The Lab of Neuroproteomics (University of Campinas, Brazil) is a multidisciplinary group that bases their investigation on psychiatric disorders in proteomics. To explain their work to the general public, they created the following video. Lab of Neuroproteomics, UNICAMP, Brazil video

Past Workshops

26th HUPO Human Brain Proteome Project Workshop
During the HUPO 2016 congress in Taipei, Taiwan

25th HUPO Human Brain Proteome Project Workshop
May 3-4, 2016 in Stockholm, Sweden
A summary of the HBPP workshop can be seen here.

27th HUPO Human Brain Proteome Project Workshop
May 9-10, 2017 in Bochum, Germany

28th The Human Brain Proteome Project (HBPP) Workshop
May 8-9, 2018 in Adelaide, Australia. 

The South Australian Health and Medical Research Institute (SAHMRI) 

For more information or participation opportunities please contact office(at)hupo.org.

Copyright 2016 - HUPO

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