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  • Odense, Denmark - Post Doc Postition in Characterization of Non-Alcoholic SteatopHepatitis (NASH) USing Clinical Proteomics and PTMomics at Department of Biochemistry and Molecular Biology, SDU

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Odense, Denmark - Post Doc Postition in Characterization of Non-Alcoholic SteatopHepatitis (NASH) USing Clinical Proteomics and PTMomics at Department of Biochemistry and Molecular Biology, SDU

25 Jan 2019 1:51 PM | Anonymous member (Administrator)

The University of Southern Denmark: Postdoc Position in Characterization of Non-Alcoholic SteatoHepatitis (NASH) Using Clinical Proteomics and PTMomics at Department of Biochemistry and Molecular Biology

Main objectives of the postdoc project (three years):

  • To identify circulating proteins (or specific PTMs) that correlate with key features of liver histopathology, primarily fibrosis, inflammation and/or hepatocyte ballooning, in the context of NASH in rodent and/or hepatocellular or liver tissue ex vivo models.
  • To explore the biological mechanism/s of action of key factor/s in the pathogenesis or resolution of NASH in in vitro and/or in vivo models.
  • To validate these factor/s in human clinical cohorts to determine their predictive validity in identifying NASH patients and/or with NASH resolution in clinical trial cohorts or subsets of human subjects.
  • To perform methodological developments within the clinical proteomics field and in PTMomics characterization of cellular signalling pathways.

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Deadline: 1 March 2019




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