Péter Horvatovich, University of Groningen, Netherlands
The dark proteome is defined accordingly to the HPP as “a colloquial term that includes missing proteins (PE2 – PE4), uncertain/dubious predicted proteins (PE5), uPE1 proteins, smORF (small proteins), and any proteins translated by long non-coding RNAs or uncharacterized transcripts including those arising from non-coding regions of DNA and/or novel alternative splicing.” The central theme of the 21st C-HPP symposium is “Illuminating the Dark proteome” and will take place in May 12-14, 2019 in Saint Malo (France) at the Hotel France & Chateaubriand, which is located inside the fortified city.
The program is currently available online on the home page of the event and on the C-HPP Wiki. The program – among others – includes discussion of the version 3.0 of Human Proteome Project Data Interpretation Guidelines, updates on neXtProt, PeptideAtlas, progress on neXt-CP50 and neXt-MP50 challenges. Key-note lectures will be provided by:
Nuno Bandeira (University of California, San Diego) on “ProteinExplorer: integration of community-scale big data for assessment of protein existence
Anne-Claude Gingras (Lunenfeld-Tanenbaum Research Institute,Toronto, Canada) on “Dark proteome: shedding light on localization and interaction of uncharacterized proteins”
Yves Vandenbrouck (CEA Grenoble, France) on “Exploring the dark side of the Human proteome using the ProteoRE platform”
Marie-Christine Birling (IMPC, Strasbourg, France) on “The virtuous cycle of human genetics and mouse (and rat) models”
Besides C-HPP, B/D HPP PIC and young investigators will contribute to the program. Places are limited, but registration for the workshop is still possible online using a registration form. The hotel block has been completely filled, but we are hoping to free some more rooms from the hotel stock available till first week of April. However, this is uncertain and in that case another hotel will have to be sought by the registrants.
The organisers Charles Pineau, Chris Overall, Young-Ki Paik, Lydie Lane are looking forward to receive all C-HPP members and all interested participants from B/D-HPP and HUPO membership.