The HPP aims to encourage all participants/authors to uphold rigorous
standards for publication and dissemination of results. All data are to
be submitted to a ProteomeXchange public data repository, statistical
analyses are to be performed to a high standard, and claims of detection
of "missing proteins" or novel coding elements require detailed
evidence. The first set of HPP data interpretation guidelines were
approved by the HPP in 2012. Version 2.0 of the guidelines was approved
in 2015, and a minor substantive update was applied as version 2.1 in July
2016. A Version 3.0 of the guidelines was released in
October 2019. These newest guidelines should be applied to all
subsequent manuscripts and data contributions from release.
IMPORTANT NOTE: If your manuscript is being submitted to JPR for the HPP special issue, the JPR guidelines also apply. In cases where the JPR guidelines and these HPP guidelines conflict, the HPP guidelines are more stringent in all cases and take precedence over the JPR guidelines. See the Current JPR Guidelines.
2016 Guidelines (Deprecated):
-
Obsolete HPP Data Interpretation Guidelines version 2.1 [PDF] - 2016-07-28
-
Changelog:
Version 2.1 has been updated in response to the review of the
manuscript accompanying these guidelines. Guideline 2 has been altered
such that deposition of data in a ProteomeXchange repository must now
occur prior to submission of a manuscript rather than prior to review of
the manuscript. Guideline 15 was updated to clarify that the two
uniquely mapping peptides of length >=9 amino acids may not be fully
nested (i.e. one peptide occurring within the other). This was
previously intended and implemented in neXtProt and PeptideAtlas, but
was not explicit in the checklist.
-
Obsolete HPP Data Interpretation Guidelines version 2.0.4 PDF] - 2016-05-06
- Changelog: Version 2.0.4 has been updated with new url for the neXtProt unicity checker.
- Obsolete HPP Data Interpretation Guidelines version 2.0.3 [PDF] - 2016-04-30
- Changelog:
Version 2.0.3 has been updated with minor wording changes as the
companion manuscript is being prepared. The requirements of the
guidelines themselves are not different from 2.0.0. A URL for the
neXtProt unicity checker tool has been added.
- Obsolete HPP Data Interpretation Guidelines version 2.0.2 [PDF] - 2016-03-22
- Changelog:
Version 2.0.2 has been updated with minor wording changes as the
companion manuscript is being prepared. The requirements of the
guidelines themselves are not different from 2.0.0.
- Obsolete HPP Data Interpretation Guidelines version 2.0.1 [PDF] - 2015-12-07
- Changelog:
Version 2.0.1 has been updated with minor wording changes contributed
by HPP leaders. The requirements of the guidelines themselves are not
different from 2.0.0.
- Obsolete 2015 HPP Data Interpretation Guidelines version 2.0.0 [PDF] - 2015-11-12
2012 Guidelines (Deprecated):
The
2012 HPP Guidelines were in effect for 3 years and are still mentioned
here, but are now considered obsolete. Please apply the current
guidelines to efforts for new contributions.
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