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Postdoctoral Position
(salary level TV-L E13, 100%)
in the field of mass spectrometry-based proteomics

This fixed-term post is available for three years, with the possibility of renewal. Currently, the regular working time for full employment is 39 hours and 50 minutes per week. All posts can, as a rule, also be filled as part-time positions if there are no compelling work-related reasons against doing so.

The group of Prof Dr Finkemeier (go.wwu.de/agfinkemeier) is seeking a highly motivated and talented scientist with excellent skills in the identification of peptides and proteins using liquid chromatography tandem mass spectrometry techniques (LC-MS/MS). The tasks include sample preparation, method development, instrument maintenance, as well as data acquisition (Q Exactive HF), data interpretation (using MaxQuant, Skyline, Proteome Discoverer, R, Perseus and others), and teaching and training of students. The successful candidate is expected to develop and implement new advances in technology and bioinformatics relevant to mass spectrometrybased proteomics and to coordinate the collaborative projects of the group. The candidate will develop their own research project within the scope of the research interests of the group, for example to unravel the functions of post-translational modifications for cell physiology and their modifying enzymes (e.g., Hart el. al. (2017) Mol Sys Biol).

Qualifications

Applicants should have a doctoral degree in biology or biochemistry with proven experience in operation and maintenance of nano-LC systems, acquisition of LC-MS data for peptides and maintenance of a mass spectrometry system (ideally Q Exactive). They should also have experience in using database searching algorithms for peptide identification, performing basic bioinformatics data analyses, and conducting protein purifications and basic biochemical techniques. Previous work on post-translational modification profiling and relative quantification of proteomes, including label-free, isotope dimethyl labeling and TMT, is beneficial. Also important are excellent organization, good interpersonal and effective communications skills, and the ability to work independently as well as on a team. Applicants should be able to accommodate a flexible work schedule. Excellent English and German language skills are required. International postdoc experience is also advantageous.

What they offer

The successful candidate will join an international and collaborative team in an excellent scientific environment. The workplace is located in the centre of Münster, easily accessible by public transport.

Application

Please apply by email and submit a single PDF document, in English or German, that includes a detailed CV, a letter of motivation, degree certificates, and the names/email addresses of two potential references. Applications should be sent by 25 November 2018 to the Institute’s secretary: maren.vennemann@uni-muenster.de 

The University of Münster is an equal opportunity employer and is committed to increasing the proportion of women academics. Consequently, it actively encourage applications by women. Female candidates with equivalent qualifications and academic achievements will be preferentially considered within the framework of the legal possibilities. The University also welcomes applications from candidates with severe disabilities. Disabled candidates with equivalent qualifications will be preferentially considered.

Click here to see the position online.

There is an opening for a postdoctoral position (or Assistant Research Scientist) to perform biological mass spectrometry in collaboration with a number of outstanding investigators at the New York University School of Medicine and neighboring universities. The position will afford the opportunity to use quantitative mass spectrometry tools such as SILAC and TMT to study cell signaling in neurons. Other possible projects include the characterization of posttranslational modifications in neuronal proteins, characterization of biomarkers for neurodegenerative disease and cancer, and the identification and characterization of small molecules that are important for cell signaling and metabolism. The lab is equipped with a nanoflow LC-Thermo Electron LTQ-Orbitrap system, three ThermoFisher Q-Exactive mass spectrometers (including HF and HF-X), and a Bruker Autoflex MALDI-TOF. The ideal candidate will have a Ph.D. in Biochemistry, Chemistry or Cell Biology with some experience in protein and/or small molecule purification/characterization and/or biological mass spectrometry and experience and/or interest in molecular neuroscience. Especially well qualified Masters level scientists will also be considered for the position.

Please address questions and/or a CV including the names of 3 references by e-mail to:

Thomas A. Neubert, Ph.D.
Professor and Director, NYU Protein Mass Spectrometry Core for Neuroscience
Skirball Institute of Biomolecular Medicine
New York University School of Medicine

office telephone: (212) 263-7265
fax: (212) 263-8214
e-mail: thomas.neubert@med.nyu.edu

For more information about the lab click here. 

NYU School of Medicine is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply.

Posting Title: Proteomics & Protein Mass Spectrometry Scientist

Job Description

The Analytical Science & Imaging Department is looking for a highly motivated scientist with experience in protein mass spectrometry/quantitative proteomics to be part of a proteomics team committed to support innovative drug discovery efforts. The successful candidate will work in a matrix team environment, performing LC/MS based proteomics experiments to answer key scientific questions from NIBR project teams. Qualified candidates will possess a M.S. degree in analytical chemistry, biology or related field with at least 5 years of working experience of protein mass spectrometry and proteomics. This candidate will be responsible for independently conducting experiments from sample preparation, LC-MS/MS to data analysis & interpretation. They are looking for a candidate who can utilize strong technical and organizational skills and has an enthusiastic, collaborative spirit.

Direct interaction with project teams, ability to translate key scientific questions to essential proteomics experiments, design the study jointly with project team collaborators. Perform the proteomics study independently. Deliver impact.

Click here to read full job description. 

The Department of Pharmacology at the University of North Carolina at Chapel Hill (https://www.med.unc.edu/pharm) invites applications for a Research Associate position in the UNC Proteomics Core Facility. The facility provides proteomics support on a fee-for-service basis for research groups at UNC and external researchers across the United States. The facility is seeking a Research Associate with extensive experience in mass spectrometry-based proteomics. The Research Associate will work closely with the Facility Director and will be responsible for:

- Preparing samples for proteomics analyses (including sample clean-up and fractionation, in-solution & in-gel protein digestion, TMT labeling, phosphopeptide enrichment).

- Analyzing complex qualitative/quantitative proteomic datasets through a variety of software packages (Proteome Discoverer, MaxQuant, Perseus, Scaffold, Skyline, IPA).

- Operating instruments and assisting with calibration, troubleshooting and maintenance. Current instrumentation includes: Thermo QExactive HF (2), Thermo Easy nLC 1200 (2), Thermo LTQ-Orbitrap Velos, Waters NanoAcquity, and a Sciex 5800 MALDI-TOF/TOF.

- Leading method development efforts to expand the core facility’s capabilities.

- Preparing reports and contributing to manuscripts.

- Participating in scientific discussions and collaborative meetings.

The successful applicant will have a PhD or MS degree in Chemistry, Biochemistry, Pharmacology or another life sciences discipline with a minimum of 4 years post-bachelor’s degree experience in mass spectrometry-based proteomics. Experience with operating LC-MS instruments, preparing proteomics samples, and analyzing complex proteomics datasets is required. Strong problem solving skills, interpersonal skills and the ability to work independently is required. The successful applicant should have a working knowledge of cell biology and common biochemical techniques. Experience with MALDI-TOF, PTM analysis, statistical/bioinformatics analysis, and targeted quantitation using multiple reaction monitoring (MRM) is a plus.

Interested candidates should submit their application online at: https://unc.peopleadmin.com/postings/147064

More information about the facility can be found at proteomics.unc.edu.
For more information about the position, please contact: Laura Herring, PhD, Research Assistant Professor,UNC Proteomics Facility Director Email: laura_herring@med.unc.edu

The University of North Carolina at Chapel Hill is an equal opportunity employer that welcomes all to apply, including protected veterans and individuals with disabilities.