Dr. Pavel Sinitcyn
Morgridge Institute For Research, United States
Pavel Sinitcyn is a distinguished Morgridge Interdisciplinary Postdoctoral Fellow at University of Wisconsin-Madison, conducting cutting-edge research in Dr.Joshua Coon’s lab. With a strong background in developing software solutions for proteomics data processing, Dr. Sinitcyn has played a pivotal role in developing tools such as MaxQuant, MaxDIA, Perseus, and Deep Proteomic Sequencing Methods.
Dr. Pavel Sinitcyn was a finalist in the HUPO 2023 ECR Manuscript Competition, for which he presented his manuscript, “Global Detection of Human Variants and Isoforms by Deep Proteome Sequencing”, in a plenary session. To get the inside story, we asked Dr. Sinitcyn a few questions about his experience in the competition. Read what he had to say below!
1. What is your current position and affiliation?
I am a postdoctoral researcher in the Coon lab at University of Wisconsin-Madison, United States. In June 2024, I will be starting my own group at Utrecht University in The Netherlands
2. How would you like your work to contribute to the field of proteomics?
I would like to see a change in the definition of protein coverage in the field. Rather than merely discussing protein coverage as the number of detected proteins out of the many annotated protein-coding genes, we should consider coverage as the portion of amino acids covered by a few detected peptides. This shift will enable a more comprehensive quantitative measurement of sequence isoforms, small amino acid variations, and post-translational modifications on a global scale.
3. What have you found in the HUPO community/congress?
I greatly appreciate the international mindset of the HUPO community. This conference goes beyond the opportunity to listen to great talks/posters and meet colleagues and friends in one place; it allows for the exploration of the landscape of the field on a global scale, spanning various countries and regions.
4. How was your experience/what did it mean to present your work at HUPO?
I thoroughly enjoyed my experience presenting my work at HUPO, especially within the HUPO ECR community. Returning to HUPO is always a pleasure. The conference's well-tuned schedule and scale allowed for a comprehensive experience without the usual need to constantly choose between simultaneous must-visit sessions. The vibrant atmosphere of the poster session and bioinformatics hub added to the overall positive experience. And finally, attending this conference was particularly meaningful for me as it was the first one after the birth of my son, giving me the opportunity to fully participate in the session organized by Moms in Proteomics.
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